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目录产品 » 稳定细胞系 » Mouse Recombinant PD-1 Stable Cell Line
CHO-K1/ Mouse PD-1 Stable Cell Line

Figure 1. FACS analysis of mouse PD-1 expression in CHO-K1/mPD-1 cells.

CHO-K1/ mouse PD-1 Stable Cell Line

Programmed cell death protein 1, also known as PD-1 and CD279 (cluster of differentiation 279), is a protein that in humans is encoded by the PDCD1 gene.PD-1, functioning as an immune checkpoint, plays an important role in down regulating the immune system by preventing the activation of T-cells, which in turn reduces autoimmunity and promotes self-tolerance. The inhibitory effect of PD-1 is accomplished through a dual mechanism of promoting apoptosis (programmed cell death) in antigen specific T-cells in lymph nodes while simultaneously reducing apoptosis in regulatory T cells (suppressor T cells).
M00552
￥85000

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Description

Programmed cell death protein 1, also known as PD-1 and CD279 (cluster of differentiation 279), is a protein that in humans is encoded by the PDCD1 gene.PD-1, functioning as an immune checkpoint, plays an important role in down regulating the immune system by preventing the activation of T-cells, which in turn reduces autoimmunity and promotes self-tolerance. The inhibitory effect of PD-1 is accomplished through a dual mechanism of promoting apoptosis (programmed cell death) in antigen specific T-cells in lymph nodes while simultaneously reducing apoptosis in regulatory T cells (suppressor T cells).
Applications Binding assay or use as immunogen

Storage Liquid nitrogen immediately upon receipt
Species Mouse
Stability 15 passages

Freeze Medium 95% complete growth medium, 5% DMSO
Culture Medium F12K, 10% FBS, 8μg/ml Puromycin

  • CHO-K1/ Mouse PD-1 Stable Cell Line
    • CHO-K1/ Mouse PD-1 Stable Cell Line

    Figure 1. FACS analysis of mouse PD-1 expression in CHO-K1/mPD-1 cells.


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