凯发一触即发

至今,GenScript的服务及产品已被Cell, Nature, Science, PNAS等1300多家生物医药类杂志引用近万次,处于行业领先水平。NIH、哈佛、耶鲁、斯坦福、普林斯顿、杜克大学等约400家全球著名机构使用GenScript的基因合成、多肽服务、抗体服务和蛋白服务等成功地发表科研成果,再次证明GenScript 有能力帮助业内科学家Make research easy.

A Comparison of the Ability of Leu- and Pro-Oxytocin to Regulate Intracellular Ca and Ca-Activated K Channels at Human and Marmoset Oxytocin Receptors

Mol. Pharmacol.. 2019; 
PierceMarsha L, MehrotraSuneet, MustoeAaryn C, FrenchJeffrey A, MurrayThom
Products/Services Used Details Operation
Stable Cell Lines … Corresponding Author: Thomas F. Murray, Department of Pharmacology, Creighton University School of Medicine, 2500 California Plaza, Omaha, NE, 68178, USA Phone: 402- 280-4076 … CHO-K1 cell lines were purchased from Genscript (M00195). Marmoset oxytocin … Get A Quote

摘要

The neurohypophyseal hormone oxytocin (OT) regulates biologic functions in both peripheral tissues and the central nervous system. In the central nervous system, OT influences social processes, including peer relationships, maternal-infant bonding, and affiliative social relationships. In mammals, the nonapeptide OT structure is highly conserved with leucine in the eighth position (Leu-OT). In marmosets (), a nonsynonymous nucleotide substitution in the gene codes for proline in the eighth residue position (Pro-OT). OT binds to its cognate G protein-coupled receptor (OTR) and exerts diverse effects, including stimulation (G) or inhibition (G) of adenylyl cyclase, stimulation of potassium channe... More

关键词