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Cecal Ligation and Puncture Alters Glucocorticoid Receptor Expression.

Crit. Care Med.. 2018; 
AbrahamMabel N,JimenezDaniela M,FernandesTiago D,DeutschmanCliffo
Products/Services Used Details Operation
Monoclonal mouse antibody (THE β-Actin) was used as an additional loading control (A00702; Genscript, Piscataway, NJ).

摘要

Interventional trials on glucocorticoids in sepsis have yielded capricious results. Recent studies have identified multiple glucocorticoid receptor isoforms. The relative abundance of these isoforms in septic patients and following murine cecal ligation and puncture is unknown. The objective of this study is to determine the effects of cecal ligation and puncture on glucocorticoid receptor isoform abundance.

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