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Causal Relationship Between Anti-TPO IgE and Chronic Urticaria by and Tests.

Allergy Asthma Immunol Res. 2019;

SánchezJorge，SánchezAndres，CardonaRic

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	… Intradermal and SPT. Recombinant TPO was used for serum and skin tests. The protein solutions were treated with LPS-Free (Toxin eraser Kit, Genscript Cat. No. L00338) and were prepared at 25.0 ng/µL in 50.0% glycerol, 0.4% phenol, and filtered using a 0.22-µm filter …

摘要

Immunoglobulin (Ig) E autoantibodies against thyroid antigens such as thyroid peroxidase (TPO) have been demonstrated in chronic spontaneous urticaria (CSU) patients in higher frequency than healthy subjects. However， if these IgE autoantibodies can trigger urticaria is still a matter of study. The aim of this study was to investigate the relationship between concomitant IgE autoantibodies against thyroid antigens in CSU.