| Specificity |
The product is specific for Panitumumab |
| Host Species |
Rabbit |
| Immunogen |
Panitumumab |
| Conjugate |
Unconjugated |
|
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product. |
| Application |
Recommended Usage |
| ELISA |
0.001-0.1 µg/ml |
|
| Form |
Lyophilized |
| Storage Buffer |
This product is lyophilized with PBS, pH 7.2, containing 0.02% sodium azide. |
| Reconstitution |
Reconstitute the lyophilized powder with deionized water (or equivalent) to a final concentration of 0.5 mg/ml. |
| Storage Instructions |
The lyophilized product remains stable up to 1 year at -20 °C from date of receipt. Upon reconstitution, it can be stored for 2-3 weeks at 2-8 °C or for up to 12 months at -20 °C or below. Avoid repeated freezing and thawing cycles. |
| Purification |
Antigen affinity purification |
| Isotype |
Rabbit IgG |
| Clonality |
Polyclonal |
| Note |
GenScript can customize this product per customer's request including product size, buffer components, etc. |
ELISA binding of Anti-Panitumumab Antibody, pAb, Rabbit (GenScript, A02063-40) with Panitumumab.
Coating antigen: Panitumumab, 1 µg/ml.
Anti-Panitumumab Antibody, pAb, Rabbit (GenScript, A02063-40) dilution start from 1,000 ng/ml.
EC50= 5.063 ng/ml.
| Target Background |
Panitumumab with trade name Vectibix, is an FDA-approved drug for the treatment of patients with EGFR-expressing metastatic colorectal carcinoma with non-mutated (wild-type) KRAS after failure of fluoropyrimidine-, oxaliplatin- and irinotecan-containing chemotherapy regimens. It is a human monoclonal antibody. Panitumumab binds to the human EGF receptor (EGFR), preventing binding of activating ligands, such as the EGF and transforming growth factor-α. GenScript Anti-Panitumumab Antibody, pAb, Rabbit is produced from sera of a rabbit immunized with Panitumumab. |
| Synonyms |
Rabbit polyclonal to Panitumumab/Vectibix |
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.
