| Specificity |
The product is specific for Golimumab |
| Host Species |
Rabbit |
| Immunogen |
Golimumab |
| Conjugate |
Unconjugated |
|
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product. |
| Application |
Recommended Usage |
| ELISA |
0.005-0.1 µg/ml |
|
| Form |
Lyophilized |
| Storage Buffer |
This product is lyophilized with PBS, pH 7.2, containing 0.02% sodium azide. |
| Reconstitution |
Reconstitute the lyophilized powder with deionized water (or equivalent) to a final concentration of 0.5 mg/ml. |
| Storage Instructions |
The lyophilized product remains stable up to 1 year at -20 °C from date of receipt. Upon reconstitution, it can be stored for 2-3 weeks at 2-8 °C or for up to 12 months at -20 °C or below. Avoid repeated freezing and thawing cycles. |
| Purification |
Antigen affinity purification |
| Isotype |
Rabbit IgG |
| Clonality |
Polyclonal |
| Note |
GenScript can customize this product per customer's request including product size, buffer components, etc. |
ELISA binding of Anti-Golimumab Antibody, pAb, Rabbit (GenScript, A02093-40) with Golimumab.
Coating antigen: Golimumab, 1 µg/ml.
Anti-Golimumab Antibody, pAb, Rabbit (GenScript, A02093-40) dilution start from 1,000 ng/ml.
EC50= 5.433 ng/ml.
| Target Background |
Golimumab with trade name Simponi, is an FDA-approved drug for the treatment of Rheumatoid arthritis (RA), Psoriatic Arthritis (PsA), Ankylosing Spondylitis (AS) and Ulcerative Colitis (UC). It is a human IgG1κ monoclonal antibody that binds to Tumor Necrosis Factor alpha (TNF-alpha), thereby inhibiting the binding to TNFα receptors and subsequent generation of inflammatory cytokines.GenScript Anti-Golimumab Antibody, pAb, Rabbit is produced from sera of a rabbit immunized with Golimumab. |
| Synonyms |
Rabbit polyclonal to Golimumab/Simponi |
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.
