| Specificity |
This product is specific for Sarilumab |
| Host Species |
Rabbit |
| Immunogen |
Sarilumab |
| Conjugate |
Unconjugated |
|
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product. |
| Application |
Recommended Usage |
| ELISA |
0.001-0.1 µg/ml |
|
| Form |
Lyophilized |
| Storage Buffer |
This product is lyophilized with PBS, pH 7.2, containing 0.02% sodium azide. |
| Reconstitution |
Reconstitute the lyophilized powder with deionized water (or equivalent) to a final concentration of 0.5 mg/ml. |
| Storage Instructions |
The lyophilized product remains stable up to 1 year at -20 °C from date of receipt. Upon reconstitution, it can be stored for 2-3 weeks at 2-8 °C or for up to 12 months at -20 °C or below. Avoid repeated freezing and thawing cycles. |
| Purification |
Antigen affinity purification |
| Isotype |
Rabbit IgG |
| Clonality |
Polyclonal |
| Note |
GenScript can customize this product per customer's request including product size, buffer components, etc. |
ELISA binding of Anti-Sarilumab Antibody, pAb, Rabbit (GenScript, A02122-40) with Sarilumab.
Coating antigen: Sarilumab, 1 µg/ml.
Anti-Sarilumab Antibody, pAb, Rabbit (GenScript, A02122-40) dilution start from 1,000 ng/ml.
EC50= 23.67 ng/ml.
| Target Background |
Sarilumab with the trade name of Kevzara, is a human monoclonal IgG1 antibody. It binds to membrane bound and soluble interleukin 6 (IL-6) receptor forms. It was FDA-approved in for the treatment of Rheumatoid Arthritis (RA) in combination with methotrexate. GenScript Anti-Sarilumab Antibody, pAb, Rabbit is produced from sera of a rabbit immunized with Sarilumab. |
| Synonyms |
Rabbit polyclonal to Sarilumab/Kevzara |
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.
