Species |
SARS-CoV-2 |
Protein Construction |
Expressed with the mutations of A67V, del69-70, T95I, G142D, del143-145, del211, L212I, ins214EPE, G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H, T547K, D614G, H655Y, N679K, P681H.
S1 protein (Gln14-Arg685) Accession # P0DTC2 |
Poly-His |
N-term |
C-term |
|
Purity |
≥ 90% as analyzed by SDS-PAGE |
Endotoxin Level |
≤ 1 EU/μg of protein by gel clotting method |
Biological Activity |
SARS-CoV-2 Spike protein S1, Omicron Variant, His Tag can bind with human ACE2 (Cat. No.: ) in functional ELISA assay. |
Expression System |
293 Cells |
Theoretical Molecular Weight |
79 kDa |
Apparent Molecular Weight |
~117 kDa, on SDS-PAGE under reducing conditions. |
Formulation |
Supplied as a solution in PBS pH 7.4 |
Concentration |
Please refer to the COA for the specific lot. |
Storage & Stability |
Upon receiving, this product remains stable for up to 6 months at -20 °C or below. Avoid repeated freeze-thaw cycles. |
Lane 1: 1 μg of SARS-CoV-2 Spike protein S1, Omicron Variant, His Tag (Cat. No. Z03729 ) (R)
Lane 2: 1 μg of SARS-CoV-2 Spike protein S1, Omicron Variant, His Tag (Cat. No. Z03729 ) (NR)
≥ 90% as analyzed by SDS-PAGE
Immobilized ACE-2 Fc Chimera, Human (Cat. No. Z03516) at 10 μg/mL can bind SARS-CoV-2 Spike protein S1, Omicron Variant, His Tag (Cat. No. Z03729 ) with a serial dilution.
THE™ His Tag Antibody [HRP], mAb, Mouse (Cat.No.A00612) is used as a secondary antibody (0.2 μg/mL).
Target Background |
SARS-CoV-2 (Severe Acute Respiratory
Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold to severe diseases. Recently, the new B.1.1.529 variant was confirmed in South Africa and preliminary evidence suggests an increased risk of reinfection with this variant. The B.1.1.529 variant was first reported to WHO on 24 November 2021 and WHO has designated this variant as a VOC (Variant of Concern), named Omicron. There are more than 30 mutations in the spike protein. |
Synonyms |
B.1.1.529; Omicron variant |
References |
1. .
2. . |
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.