凯发一触即发

至今,GenScript的服务及产品已被Cell, Nature, Science, PNAS等1300多家生物医药类杂志引用近万次,处于行业领先水平。NIH、哈佛、耶鲁、斯坦福、普林斯顿、杜克大学等约400家全球著名机构使用GenScript的基因合成、多肽服务、抗体服务和蛋白服务等成功地发表科研成果,再次证明GenScript 有能力帮助业内科学家Make research easy.

Effects of sevoflurane exposure during different stages of pregnancy on the brain development of rat offspring

J Anesth. 2021-07; 
Feng-He Cui, Jie Li, Ke-Zhong Li, Yong-Gang Xie, Xiao-Ling Zhao
Products/Services Used Details Operation
Recombinant Proteins … ELISA kits were utilized according to the kit instructions to detect the expression of IL-1β (Z02978-1, Genscript, Guangzhou, China), TNF-α (Z02999-10, Genscript), and IL-6 (CG39, Novoprotein, Guangzhou, China) in the supernatant. Nissl staining … Get A Quote

摘要

objective: This study explored the effects of sevoflurane exposure during different stages of pregnancy on the brain development of offspring. methods: Thirty-six pregnant SD rats were randomly divided into 4 groups: control, sevoflurane exposure in early (S1) pregnancy, sevoflurane exposure in middle (S2) pregnancy, and sevoflurane exposure in late (S3) pregnancy. After natural birth, the learning and memory capacity of offspring rats was analyzed using the Morris water maze experiment. The hippocampi of offspring rats were collected. The levels of interleukin (IL)-1β, IL-6, and tumor necrosis factor (TNF)-α in the hippocampus were measured by ELISA. Additionally, the Nissl bodies in the hippocampus were ana... More

关键词

NR4A1/NF-κB pathway, Offspring, Pregnancy, Sevoflurane